Cataract surgery with triple-DMEK for Fuchs dystrophy
Part of Eyes & vision, Genetic & congenital clinical trials.
This trial tests a combined surgery that treats both cataract and Fuchs endothelial corneal dystrophy at the same time. It compares the standard cataract surgery to one that also replaces the damaged cornea layer, aiming to improve vision with fewer steps.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have both Fuchs corneal dystrophy and a cataract in one eye.
- You are at least 18 years old.
- Your cataract is moderate (grade 2 or 3) and your cornea has changes without swelling.
- Your vision is between 20/32 and 20/100 (not too good or too bad).
- You have not had cataract or corneal surgery on the other eye.
- You can understand and read the study language (English or local language).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This Phase 3 trial compares outcomes from two cornea transplant procedures in people with FECD, a disease that makes the cornea swell and affect vision. It may help you and others by identifying which approach best supports clear vision and stable corneal thickness after surgery.
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This study looks at how the cornea (the clear front part of the eye) changes after cataract surgery in people with Fuchs' endothelial dystrophy, a condition that affects the inner layer of the cornea. It compares them to people without this condition to see if there are differences in corneal thickness after surgery.
This trial tests an investigational eye drop (DT-168) in people with Fuchs endothelial corneal dystrophy who are already scheduled for a corneal transplant. The goal is to see if DT-168 can improve outcomes or delay the need for surgery.
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