Stem cell injection for chronic radiation proctitis
Treatments studied
Part of Cancer, Digestive system clinical trials.
This study tests whether a single injection of special cells (umbilical cord stem cells) can help heal long-term inflammation in the rectum caused by previous pelvic radiation. It's for people whose standard treatments have not worked.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18–79 years old and able to handle daily activities with little or no help.
- You had radiation for a pelvic cancer (like cervix, prostate, or rectum) and now have ongoing rectal inflammation (proctitis) that started at least 6 months after treatment.
- Standard treatments for this proctitis haven't worked for you.
- You do not have severe organ problems (like liver, kidney, or heart failure) or a serious immune disease.
- Your cancer has not returned or spread, and you aren't currently pregnant.
- You agree not to try to conceive and to use effective birth control during the study and for 6 months after.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether a special type of stem cells (from umbilical cord blood) can help heal chronic bowel damage caused by radiation therapy. It is for people whose bowel symptoms, like diarrhea or pain, continue despite standard treatment.
This trial tests whether a special kind of stem cell (called TH-SC01) can help people with long-term rectal damage from pelvic radiation. You will be injected with a small amount of radioactive material attached to the cells so doctors can see where they go and how long they stay in your body.
This study tests a new treatment for radiation cystitis, a bladder condition caused by past pelvic radiation. It combines stem-cell derived particles with a standard bladder instillation to see if it helps improve symptoms like urgency or blood in urine.
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