Chemo for prostate cancer with DNA repair changes
Treatments studied
Part of Cancer, Kidney & urinary clinical trials.
This trial tests a combination of two chemotherapy drugs (carboplatin and docetaxel) for men whose prostate cancer has spread and has specific changes in DNA repair genes. It aims to see if this treatment can help when other hormone therapies have stopped working.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have prostate cancer that has spread to other parts of the body.
- You have already tried a hormone therapy like abiraterone or enzalutamide.
- A genetic test shows a change in one of a specific set of DNA repair genes (like BRCA1, BRCA2, or ATM).
- You have not had platinum or taxane chemotherapy for prostate cancer before (some exceptions apply).
- You are 18 or older and in generally good health (able to care for yourself).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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