Oxycodone for long-term pain relief in ICU patients
Treatments studied
Part of Brain & nervous system clinical trials.
This trial tests a pain medicine called oxycodone for patients on breathing machines in the ICU. It aims to see if it provides safe and effective long-term pain control.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You are on a breathing machine (ventilator) for less than 3 days before starting the study.
- Your doctor expects you to need the breathing machine for at least another 24 hours.
- You do not have severe kidney or liver disease.
- You are not in deep sedation or requiring very strong blood pressure medicine.
- You have not been taking strong opioids (like morphine) for chronic pain.
- You are not pregnant, breastfeeding, or have a history of drug or alcohol abuse.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a pain medicine called hydromorphone for people in the ICU who need a breathing tube. The goal is to see how well it works and if it's safe for managing pain and sedation.
This trial tests a new pain and sedation medicine called Oliceridine for patients in the ICU who are on a breathing machine. It aims to see if it works safely and effectively to help you stay comfortable.
This study tests adding extra pain medicines (acetaminophen or an NSAID) to usual opioid pain treatment for children on a breathing machine. The goal is to find the safest and most effective way to manage pain.
This trial tests if giving two pain medicines before surgery can stop short-term pain from becoming chronic. It may help people having major abdominal surgery with a breathing tube.
This trial compares two medicines, methadone and remifentanil, to see which one works better for pain after brain surgery. It may help improve your recovery and comfort.
This study looks at how the sedative remifentanil works in critically ill patients who are underweight or normal weight. It aims to find the right dose for these patients while they are on a breathing machine in the ICU.
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