Pain control after brain surgery: methadone vs remifentanil
Treatments studied
Part of Brain & nervous system, Cancer, Injuries & trauma, Pain clinical trials.
This trial compares two medicines, methadone and remifentanil, to see which one works better for pain after brain surgery. It may help improve your recovery and comfort.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You are having brain surgery (specifically on the upper part of the brain).
- Your weight and height put your body mass index (BMI) between 18.5 and 45.
- You can understand and read English.
- You do not have chronic pain that requires daily strong painkillers (like fentanyl patch or oxycontin).
- You have not used methadone recently and are not allergic to it.
- You do not have active or past substance use disorder currently treated with medications like methadone, buprenorphine, or naltrexone.
- You do not have serious kidney or liver problems.
- You are not pregnant.
- You do not use oxygen at home for lung disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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