Clinical trials
Pregnancy, High Risk clinical trials
Below are recruiting pregnancy, high risk clinical trials, each written for real people, not researchers. We’re tracking 367 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07774949Recruiting
Thyroid and anxiety effects on baby heart rate in high-risk pregnancy
This study looks at how thyroid function and anxiety in mothers might affect the baby's heart rate patterns (shown on a non-stress test) in high-risk pregnancies. The goal is to help doctors better understand and support high-risk pregnancies.
IstanbulAges 18–45 - NCT07774936Recruiting
Emotional factors and fetal monitoring in high-risk pregnancies
This study looks at how a pregnant person's feelings of control over their health and their anxiety levels relate to the results of a non-stress test (NST), which checks the baby's heartbeat and movements. It aims to improve care for high-risk pregnancies.
IstanbulAges 18–45 - NCT06275568Recruiting
Healthy food support for high-risk pregnant women
This trial tests a program that helps pregnant women at high risk get healthy food. It uses a special card from a partner (About Fresh) to make it easier to eat well during pregnancy.
Houston, TexasAges 18 years+ - NCT05035160Recruiting
Join a pregnancy tissue and sample study for research
This study collects and stores samples from pregnancy, birth, or after delivery to help researchers learn from perinatal health information. It may help future care by building a high-quality repository of biospecimens and related data.
Los Angeles, CaliforniaAges 1 minute+ - NCT07124325Recruiting
Home baby heart monitoring for high-risk pregnancy
This trial lets you monitor your baby's heartbeat at home with a simple device instead of coming to the hospital each time. It's for women with certain high-risk pregnancy conditions who are 32 weeks or more along.
BirminghamAges 18 years+ - NCT07001332Recruiting
High-risk heart stent procedure study
This study tests a new device to help people with high-risk blockages in their heart arteries during a stent procedure. It compares the new device to standard treatment to see if it is safe and effective.
Phoenix, ArizonaAges 18–88 - NCT06497205Recruiting
Monitoring fetal heart activity in pregnancy
This trial tests a new wearable device to monitor your baby's heart activity during pregnancy. It aims to see if this device works well for both low and high-risk pregnancies to detect any heart issues early.
London, TootingAges 18–50 - NCT05827549RecruitingPhase 2
Blinatumomab for relapsed ALL, matched by risk group
This Phase 2 study tests how well blinatumomab works for children and adults whose acute lymphoblastic leukemia (ALL) has come back. It also looks at whether results differ based on the patient’s relapse “risk group.”
DaeguAges 1–22 - NCT03152058RecruitingPhase 2
Certolizumab for pregnancy in people with APS
This Phase 2 study tests whether certolizumab can improve pregnancy outcomes in people with antiphospholipid syndrome (APS). It targets pregnancy complications related to APS while closely checking safety, infections, and certain health conditions.
New York, New YorkAges 18–40 - NCT03775954Recruiting
Fetal heart testing in high-risk pregnancies after baby loss
This study checks unborn babies’ heart signals using special scans during pregnancy and then checks the baby’s heart shortly after birth. It may help researchers understand why certain high-risk pregnancies can lead to fetal demise and improve care.
Madison, WisconsinAges 18 years+ - NCT03896269RecruitingPhase 1
CPX-351 for high-risk MDS or CMML that came back
This Phase 1 trial studies CPX-351, a cancer medicine, in people with high-risk myelodysplastic syndrome (MDS) or chronic myelomonocytic leukemia (CMML) whose disease relapsed or did not respond to prior treatment. It may help shrink or control the leukemia and improve blood counts in patients who cannot or do not want a stem cell transplant.
Houston, TexasAges 18 years+ - NCT04047641RecruitingPhase 1/Phase 2
Quizartinib with chemotherapy for new or returning leukemia
This trial tests a combination of anti-leukemia drugs (including quizartinib) together with chemotherapy for people with acute myeloid leukemia (AML), a rare mixed-type leukemia, or high-risk myelodysplastic syndrome (MDS). It may help by trying to better control cancer in people whose disease is newly diagnosed or has returned/not responded to prior treatment.
Houston, TexasAges 18 years+ - NCT04783597Recruiting
Predict preeclampsia using blood vessel stiffness in pregnancy
This study looks for ways to predict preeclampsia (a pregnancy complication that can raise blood pressure and harm organs) early by measuring how stiff certain blood vessels are. If you’re considered higher risk, this could help identify problems sooner so your care team can watch you more closely.
Montreal, QuebecAges 18 years+ - NCT05013216RecruitingPhase 1
Vaccine trial for people at high risk of pancreatic cancer
This early-phase trial studies a long-peptide vaccine designed for people with certain genetic changes that raise the risk of pancreatic cancer. The goal is to help your immune system recognize and respond to cancer-related changes before cancer develops.
Baltimore, MarylandAges 40 years+ - NCT05388643Recruiting
Early screening for gestational diabetes during early pregnancy
This study tests whether checking for gestational diabetes (diabetes that starts in pregnancy) early can help identify it sooner in people at higher risk. You may be asked to do a glucose test during your first prenatal visits so clinicians can monitor and respond earlier.
Worcester, MassachusettsAges 18 years+ - NCT05662462Recruiting
Phone coaching to keep blood sugar in range during pregnancy
This study tests whether technology plus coaching can help pregnant people with type 2 diabetes keep their blood sugar in a healthy target range. You may use a smartphone app and, if assigned to that group, a device that tracks glucose continuously.
Columbus, OhioAges 18 years+ - NCT05739123Recruiting
Pregnancy safety registry for relugolix-containing medicines
This is an observational study that collects real-world information about pregnancy outcomes when relugolix-containing therapy is taken during pregnancy. It aims to better understand safety for both the parent during pregnancy and the child after birth.
Wilmington, North CarolinaAges birth+ - NCT05786235Recruiting
Pregnant people with or without antiphospholipid antibodies
This study is looking at pregnancy outcomes in people who are pregnant and either have antiphospholipid antibody syndrome (APS) or do not have APS but do have prior full-term pregnancies. It may help doctors understand risks and how to manage pregnancies in these groups.
MilanAges 18–45 - NCT05790252RecruitingPhase 3
Buprenorphine patch for starting opioid treatment during pregnancy
This Phase 3 study tests whether a skin patch can help pregnant people start buprenorphine treatment for opioid use disorder safely and effectively. It may help with easier “induction” (starting the medication) while you’re pregnant.
St Louis, MissouriAges 18–110 - NCT05807256Recruiting
Fertility treatments for people with immune system joint diseases
This trial looks at fertility (“medically assisted fertilization,” such as IVF) for people with certain immune-related rheumatology conditions (like lupus, rheumatoid arthritis, or vasculitis). It may help patients and their clinicians understand which fertility approach works best and is safe for this group.
MilanAges 18–50 - NCT05909046Recruiting
Diabetes screening after childbirth and follow-up care study
This study checks how well diabetes screening done right after delivery works, and then offers follow-up care for participants later after birth. It may help you catch ongoing diabetes risk early and connect you to the right care.
Columbus, OhioAges 18 years+ - NCT06302010Recruiting
Stress ball for anxiety during high-risk pregnancy test
This study tests whether squeezing a stress ball during a non-stress test (baby heartbeat check) can help lower anxiety and improve well-being for women with high-risk pregnancies. It's for women who are at least 32 weeks pregnant.
SamsunAges 18–45 - NCT06654713Recruiting
Closed-loop insulin system impact on pregnancy study
This study looks at how automated insulin delivery systems (closed-loop pumps) work during pregnancy for women with type 1 diabetes. It aims to understand how these systems can help manage blood sugar levels safely for both you and your baby.
San Francisco, CaliforniaAges 18 years+ - NCT06700044Recruiting
Probiotics for high-risk pregnancy
This study tests whether taking a probiotic supplement during pregnancy can help prevent complications in women at risk for preeclampsia. You would take a daily probiotic or placebo pill from about 20 weeks until delivery.
LundAges 18 years+
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Pregnancy, High Risk trials by city
Studies with a site in or near these metro areas.
Pregnancy, High Risk trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for pregnancy, high risk?
- Yes. Clin2 currently lists 367 recruiting pregnancy, high risk studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a pregnancy, high risk trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a pregnancy, high risk trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.