Clin2
NCT06590259Possibly a fitRecruiting

Ablation plus drug therapy for colorectal cancer liver metastases

Colorectal Cancer Liver Metastasis

Part of Cancer, Digestive system clinical trials.

This trial tests a combination treatment that uses heat or cold (ablation) to destroy liver tumors along with medicines that boost your immune system to fight cancer. It is for people whose colorectal cancer has spread to the liver and who could not have surgery, or whose first treatment stopped working.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
20 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You are between 18 and 75 years old.
  • You have colorectal cancer that spread to the liver, and the liver tumors cannot be removed by surgery or you choose not to have surgery.
  • Your primary tumor is not causing serious problems like bleeding or blockage.
  • Your first line of treatment (the first drugs or therapies you tried) did not work or the disease got worse.
  • You have 5 or fewer liver tumors, and each tumor is no bigger than 3 cm (about 1.2 inches).
  • You are willing to receive a type of immunotherapy called anti-PD-1 (it helps your immune cells attack cancer).

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06801665Recruiting· Phase 2
Combination therapy for advanced colorectal cancer with liver spread

This trial tests a new combination of treatments for advanced colorectal cancer that has spread to the liver. It aims to see if this combination can shrink tumors and help patients live longer.

Changzhou
NCT06788171Recruiting· Phase 2
Combined therapy for colorectal cancer with liver spread

This trial tests a new combination of treatments for colorectal cancer that has spread to the liver. It combines a special type of radiation therapy (called PULSAR) with immunotherapy and chemotherapy plus a drug that targets blood vessels, to see if it helps shrink tumors and improve outcomes.

Fuzhou, Fujian
NCT04687631Recruiting· Phase 3
Study drug for colorectal cancer that spread to the liver

This Phase 3 trial tests a treatment approach for colorectal cancer that cannot be removed with surgery at first but has spread only to the liver. It is intended for people whose tumor is RAS/BRAF “wild-type” and who are well enough to do daily activities, to see if the treatment can control the cancer better.

Shanghai, Shanghai Municipality
NCT06889610Recruiting· Phase 2
Ablation plus drug therapy for advanced solid tumors

This trial tests combining a liver tumor ablation procedure with systemic drugs for people with advanced colorectal, breast, or melanoma cancer that has spread to the liver. The goal is to see if this approach can help when standard treatments have stopped working.

Shanghai
NCT07381309Not yet recruiting· Phase 2
Combination therapy for colorectal cancer that has spread to the liver

This trial tests a combination of treatments for people with colorectal cancer that has spread to the liver and cannot be removed by surgery. It uses an oncolytic virus (which infects and kills cancer cells) along with radiation, chemotherapy, targeted therapy, and immunotherapy to try to shrink the liver tumors.

Guangzhou, Guangdong
NCT07863869Not yet recruiting· Phase 1/Phase 2
Combination therapy for colorectal cancer with liver tumors

This trial is testing a combination of a new immunotherapy drug (QL1706) with chemotherapy and either cetuximab or bevacizumab for people with colorectal cancer that has spread to the liver and can potentially be removed by surgery. The goal is to shrink the tumors before surgery, making them easier to remove.

Hear when a new Colorectal Cancer Liver Metastasis trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.