Upadacitinib for Psoriatic Arthritis with Spine Involvement
Treatments studied
Part of Bones, joints & muscles, Skin clinical trials.
This study tests how well upadacitinib (a pill taken daily) works for people with active psoriatic arthritis that also affects the spine. It is for those who have not responded well enough to other treatments like NSAIDs or biologics.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be at least 18 years old.
- You have a diagnosis of psoriatic arthritis (PsA) from your rheumatologist.
- You have active inflammation or structural changes in your spine or sacroiliac joints (seen on X-ray or MRI).
- You have had chronic back pain for at least 3 months, and currently have moderate to severe symptoms (scores of 4 or more on a 0-10 scale).
- You've tried at least two different NSAIDs for a total of 4 weeks without enough relief, or you cannot take NSAIDs.
- If you are a woman who can become pregnant, you must not be pregnant or breastfeeding, and you must agree to use effective birth control during the study and for 30 days after the last dose.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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