Clin2
NCT07273656Worth exploringNot yet recruiting

Freezing plus tirbanibulin ointment for scaly spots on scalp or forehead

KeratosisActinic Keratoses

Part of Cancer, Skin clinical trials.

This trial tests whether freezing the spots (cryotherapy) followed by a medicated ointment (tirbanibulin) works better than freezing alone for actinic keratoses on the scalp and forehead. It may help you if you have many of these rough spots and want to see if the combination treatment works better.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
59 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 or older.
  • You have at least 8 actinic keratoses (rough, scaly spots) on your scalp or forehead, with at least 4 on each side.
  • You have not used tirbanibulin before.
  • In the past 6 weeks, you have not used other prescription creams or procedures for actinic keratoses on your scalp or forehead.
  • In the past 2 weeks, you have not had freezing, chemical peels, or laser resurfacing on your scalp or forehead.
  • If you could become pregnant, you agree to use effective birth control and have a negative pregnancy test.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06461442Enrolling by invitation· Phase 4
Freezing vs. cream for sun-damaged spots

This study compares two ways to treat sun-damaged spots called actinic keratoses: freezing them (cryotherapy) or applying a chemotherapy cream (5-fluorouracil). The goal is to see which works better and is safer for people with many spots on their head, neck, arms, or legs.

Sacramento, California
NCT06274320Recruiting
Testing a urea cream before actinic keratosis treatment

This trial tests whether applying a 30% urea cream (Lipikar) before Tolak® treatment helps treat actinic keratoses (rough, scaly spots) on the scalp. It may make the skin more receptive to the treatment.

Wuppertal
NCT06499415Recruiting· Phase 4
Combination cream vs standard cream for precancerous skin spots

This trial tests if adding calcipotriol to a standard chemotherapy cream (5-fluorouracil) works better than the standard cream alone for treating actinic keratosis (precancerous sun-damaged skin spots). You may qualify if you have at least four spots on your face, scalp, neck, chest, or arms.

Heerlen, Limburg
NCT06385340Recruiting
Testing Lipikar Baume AP+M for actinic keratosis

This study tests if a moisturizing cream called Lipikar Baume AP+M can help with actinic keratoses (rough, scaly spots caused by sun damage) on the forearms or backs of the hands. You'll use the cream on one arm and compare it to the other arm to see if it makes a difference.

Wuppertal, North Rhine-Westphalia
NCT07401277Recruiting· Phase 1
5-FU plus aluminum for actinic keratoses on scalp or forearms

This trial tests whether a combination of the chemotherapy cream 5-fluorouracil and an aluminum solution works well to treat actinic keratoses (precancerous sun-damaged spots) on the scalp or forearms. It may help if you have 4–15 of these spots and are generally healthy.

Morgantown, West Virginia
NCT06685588Not yet recruiting
Creams before light therapy for scalp sun spots

This trial compares two different creams used before a light-based treatment (photodynamic therapy) for actinic keratoses on the scalp. It aims to see which pre-treatment works better to clear these rough, scaly spots.

Hear when a new Actinic Keratoses trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.