Treatment for actinic keratoses after organ transplant
Part of Cancer, Skin clinical trials.
This study tests a combination of two topical creams (5-fluorouracil and calcipotriene) to treat actinic keratoses, which are rough, scaly patches on the skin that can be precancerous. You may be able to join if you have these patches and have had an organ transplant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years old or older.
- You must have between 4 and 15 visible actinic keratoses (rough, scaly patches) in one area the size of a 4-inch square on your face, scalp, or arms/hands.
- You must have had a kidney, lung, heart, liver, or pancreas transplant and be on immunosuppressive medications for at least one year before the study starts.
- You must not have active skin cancer at the start of the study.
- You must not have used certain skin treatments (like field cancerization, nicotinamide, or vitamin A derivatives) within the last 12 months in the treatment area.
- You must not be allergic to 5-fluorouracil, calcipotriene, trolamine-NF, penDerm cream base, propylene glycol, or peanuts.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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