Clin2
NCT06472037Possibly a fitRecruiting

AG chemo plus immunotherapy and short radiation for locally advanced pancreatic cancer

Locally Advanced Pancreatic Ductal Adenocarcinoma

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests a combination of two chemotherapy drugs (AG) plus an immunotherapy (cadonilimab) and a short course of radiation for people with locally advanced pancreatic cancer that hasn't been treated yet. The goal is to see if this approach helps shrink or control the tumor.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
30 people
Ages
18 years to 75 years
Study type
Interventional

Who can take part

  • You must be 18 to 75 years old.
  • You must have locally advanced pancreatic cancer confirmed by biopsy, with no prior cancer treatment like chemo, radiation, or immunotherapy.
  • Your tumor must be measurable on a CT or MRI scan.
  • You must be able to care for yourself (ECOG score 0 or 1).
  • Your blood counts, liver, kidney, and thyroid function must be within certain limits.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07101679Recruiting· Phase 2
Study of radiation, chemo, and immunotherapy for advanced pancreatic cancer

This trial tests a combination of chemotherapy (GnP), an immunotherapy drug (serplulimab), and targeted radiation (SBRT) as a first treatment for locally advanced pancreatic cancer that cannot be removed by surgery. The goal is to see if this triple therapy can shrink the tumor and improve outcomes.

Chengdu, Sichuan
NCT06405490Recruiting· Phase 2
Chemo plus immunotherapy for first-line advanced pancreatic cancer

This trial tests a combination of chemotherapy (NALIRI-XELOX) plus a newer immunotherapy drug (AK104) as a first treatment for people with advanced pancreatic cancer that hasn't been treated yet. The goal is to see if this combination works better than standard treatments.

Beijing, Beijing Municipality
NCT06454448Recruiting· Phase 1/Phase 2
Adebrelimab plus chemotherapy for advanced pancreatic cancer

This trial tests a combination of a targeted immune therapy (Adebrelimab) with three chemotherapy drugs for people with metastatic pancreatic cancer who haven't had any treatment yet. The goal is to see if this combination can shrink tumors and help people live longer.

Tianjin, Tianjin Municipality
NCT06475326Recruiting· Phase 2
Adebrelimab plus chemo for locally advanced pancreas cancer

This trial tests a new immunotherapy drug (adebrelimab) combined with a standard chemotherapy cocktail (NALIRIFOX) for people with locally advanced pancreatic cancer that cannot be removed by surgery. The goal is to see if this combination shrinks or controls the cancer better than chemo alone.

Shanghai
NCT06916975Not yet recruiting· Phase 2
Adebrelimab plus chemotherapy for advanced pancreatic cancer

This trial tests a combination of an immunotherapy drug (adebrelimab) with two chemotherapy drugs (gemcitabine and nab-paclitaxel) for people with advanced pancreatic cancer that has progressed after prior treatment. The goal is to see if adding immunotherapy can help shrink tumors or slow the cancer down.

Shanghai
NCT06359275Recruiting· Phase 2
Combination therapy for locally advanced or recurrent pancreatic cancer

This trial tests a combination of immunotherapy (PD-1), chemotherapy, and a special type of radiation called PULSAR for patients with locally advanced pancreatic cancer or cancer that has come back only in the pancreas area. The goal is to see if this approach can shrink tumors or keep them from growing.

Shanhai

Hear when a new Locally Advanced Pancreatic Ductal Adenocarcinoma trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.