Heart nerve ablation for severe fainting
Part of Brain & nervous system clinical trials.
This study tests a procedure called cardioneuroablation, which uses targeted heat (radiofrequency) to calm overactive nerves that cause your heart to beat too slowly and make you faint. The goal is to stop severe fainting spells in people with reflex syncope who haven't gotten better with other treatments.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have had severe, repeat fainting spells (reflex syncope) that are linked to a pause in your heartbeat lasting more than 3 seconds, especially if you've been injured or have had near-fainting with a very slow heartbeat.
- You must have tried non-drug treatments (like lifestyle changes or physical maneuvers) that didn't help your symptoms.
- You must have had a positive atropine test (your heart rate speeds up significantly when given the medicine atropine, without developing heart block).
- You must not have any condition that would make the procedure (cardioneuroablation) unsafe, such as active infection or bleeding problems.
- You must not have any condition that would make a CT scan with contrast dye unsafe, like severe kidney problems or an allergy to the dye.
- You must be willing and able to give written informed consent to participate.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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