Clin2
NCT06477692Possibly a fitRecruiting

Comparing Neck Radiation Options for Head and Neck Cancer

Head and Neck Cancer

Part of Cancer clinical trials.

This trial is testing whether radiation to just the lymph nodes near the tumor is as effective as treating a larger area of the neck. It is for people with certain head and neck cancers (not unknown primary or glottic) and aims to lower side effects.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
80 people
Ages
18 years to 99 years
Study type
Interventional

Who can take part

  • You have a certain type of head and neck cancer (squamous cell carcinoma) in the oropharynx, larynx, or hypopharynx.
  • You have a tumor that can be seen on a scan or exam (or you had a small lymph node removed for diagnosis).
  • Your cancer is at an early-to-advanced stage (I to IVB), but not glottic (voice box) cancer at stage I or II.
  • You are 18 or older, and in fairly good health (able to do daily activities).
  • You can have a CT or MRI of your neck, and a PET-CT scan.
  • You have not had radiation to the neck before, and your cancer has not spread to distant organs.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07241273Not yet recruiting
Guided neck radiation for one-sided throat cancer

This trial tests a new way to guide radiation treatment for a type of throat cancer that is on one side only. The goal is to see if using a special scan (SPECT-CT) to map lymph drainage can help doctors decide how to treat the neck more precisely and reduce side effects.

Brest
NCT07528495Recruiting· Phase 2/Phase 3
Skipping neck radiation for oral cancer after surgery

This trial tests whether patients with early-stage oral cancer who have surgery and lymph-node removal can skip radiation to the neck if certain favorable conditions are met. The goal is to reduce side effects like difficulty swallowing while keeping cancer control strong.

Jhajjar, Haryana
NCT06137274Recruiting· Phase 2
Adaptive radiation boost for head and neck cancer

This trial tests a new way of giving radiation therapy, called adaptive radiation boost, for people with head and neck cancer. The goal is to see if this approach can better target the cancer and possibly improve outcomes.

Tampa, Florida
NCT06472570Recruiting
Targeted radiation for head and neck tumors

This trial tests a precise type of radiation called stereotactic radiosurgery for people with head or neck tumors. It may be an option for those who need radiation or chemoradiation as their main treatment or after surgery.

Gliwice, Gliwicw
NCT07253402Recruiting
Microbiota-guided radiation therapy for head and neck cancer

This trial is testing a new way to use radiation therapy for head and neck cancer by also looking at the bacteria in your mouth and gut. The goal is to see if adjusting the treatment based on your bacteria can improve outcomes and reduce side effects.

Milan, Milan
NCT05333523Recruiting· Phase 3
Personalized neck radiation using a lymph node sentinel biopsy

This Phase 3 trial tests whether guiding neck radiation by checking the “sentinel” lymph node can target treatment more precisely in certain larynx, hypopharynx, or oropharynx cancers. It aims to improve control while potentially reducing unnecessary radiation to areas that don’t need it.

Amsterdam

Hear when a new Head and Neck Cancer trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.