Clin2
NCT07528495Possibly a fitRecruiting

Skipping neck radiation for oral cancer after surgery

Head and Neck Cancer

Treatments studied

Part of Cancer clinical trials.

This trial tests whether patients with early-stage oral cancer who have surgery and lymph-node removal can skip radiation to the neck if certain favorable conditions are met. The goal is to reduce side effects like difficulty swallowing while keeping cancer control strong.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2/Phase 3
Enrollment
396 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • Age 18–69 years old
  • Squamous cell carcinoma (the most common type) of the mouth, surgically removed with lymph-node dissection
  • At least one side of the neck had surgery with 12+ lymph nodes removed
  • Pathology shows no cancer spread to lymph nodes (N0 or N1 stage) but has high-risk features like close/positive surgical margins or nerve/vessel involvement
  • Able to attend long-term follow-up visits and complete quality-of-life surveys in English or Hindi
  • Start radiation therapy (if needed) within 6–8 weeks of surgery

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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