Calcium folinate for hereditary spastic paraplegia type 56
Treatments studied
Part of Brain & nervous system, Genetic & congenital clinical trials.
This trial tests a drug called calcium folinate (a form of vitamin B9) to see if it can help people with a rare genetic type of spastic paraplegia (SPG56). It aims to improve leg stiffness and weakness caused by a specific gene change.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a specific genetic form of hereditary spastic paraplegia called SPG56 (confirmed by a CYP2U1 gene test).
- You are willing to follow the study plan and take part in all visits.
- You are not allergic to the study drug (calcium folinate).
- You do not have another serious medical condition (like heart disease, cancer, or liver/kidney problems) from the past year.
- You are not pregnant, breastfeeding, or planning to become pregnant during the study.
- You have not taken another experimental drug in the last 30 days.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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