Study of ITB treatment for hereditary spastic paraplegia
Part of Brain & nervous system, Genetic & congenital clinical trials.
This trial tests if a treatment called ITB (intrathecal baclofen) can help reduce muscle stiffness in people with hereditary spastic paraplegia (HSP). Participants will receive the treatment and be followed over time to see how well it works.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with hereditary spastic paraplegia (HSP), based on symptoms and genetic testing
- You are between 14 and 70 years old
- You have significant muscle stiffness in at least 2 joints of your legs, rated as grade 3 or higher on the Modified Ashworth Scale
- You are willing and able to follow the study plan and attend visits
- You are not allergic to baclofen
- You are not pregnant, breastfeeding, or planning to become pregnant during the trial
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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