Why smell may change after COVID-19: a nose tissue study
Part of Brain & nervous system, Infections, Lungs & breathing clinical trials.
This study looks at why some people lose or change their sense of smell after COVID-19. Researchers will take a tiny sample of tissue from your nose to study the cells and molecules involved.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have had COVID-19 and now have lasting smell problems (like things smelling wrong or not smelling much at all).
- You must be willing to have a small biopsy (tissue sample) taken from your nasal passages for research.
- You cannot have other nose conditions (like sinusitis, polyps, or a deviated septum) that could affect your smell.
- You cannot be taking blood thinners (anticoagulants).
- You cannot be allergic to numbing medicines (local anesthetics).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new way of doing smell training to help people whose sense of smell has not recovered after a viral illness. It may help you smell things better again.
This study looks at why sense of smell changes as people get older. By participating, you may help researchers better understand smell loss in aging, which could lead to earlier detection of health issues.
This study tests how smell testing might affect your health and wellbeing. You will participate in sessions online or at community events where your sense of smell is evaluated.
This study is looking at how the brain processes smells in people with chronic sinusitis and nasal polyps who have a reduced sense of smell. It will compare brain images (MRI) of patients who are starting biologic treatment and those who are not, to understand how these medications might affect the brain.
This study tests a special smell training program to see if it helps improve your sense of smell after sinus surgery. The training involves regularly smelling different scents to help your nose recover.
This study looks at why people with nasal polyps lose their sense of smell and how it might come back. You may be able to join if you have had nasal blockage, runny nose, smell loss, or facial pain for at least 12 weeks, have polyps seen inside your nose, and are using a steroid spray regularly.
Hear when a new Covid19 trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.