Brain activity and smell loss in chronic sinusitis treated with biologics
Part of Ear, nose & throat, Immune system & allergy clinical trials.
This study is looking at how the brain processes smells in people with chronic sinusitis and nasal polyps who have a reduced sense of smell. It will compare brain images (MRI) of patients who are starting biologic treatment and those who are not, to understand how these medications might affect the brain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years of age or older.
- You have a decreased sense of smell (diagnosed with a smell test).
- You are eligible for biologic medications to treat your chronic sinusitis with nasal polyps.
- You either have not yet started biologic treatment, or you received your first injection within the last 48 hours.
- Your smell loss is not caused by other conditions like head injury, sinus surgery, tumors, recent infections, or neurological/psychiatric disease.
- You can safely undergo an MRI (no magnetic metal implants, no metal fragments, not pregnant, not severely claustrophobic)
- You can understand Danish.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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