Testing a new drug for severe leg artery disease
Part of Heart & circulation clinical trials.
This trial tests an experimental drug for people with critical limb ischemia, a serious condition where not enough blood reaches the legs. It aims to see if the drug can help with pain or healing of leg ulcers without the need for surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with critical limb ischemia (severe leg pain at rest or non-healing sores on your leg or foot).
- You are not able to have surgery to fix the blood flow, or previous surgery didn't work, or you choose not to have surgery.
- You are currently taking standard blood-thinning and blood vessel-widening medicines for at least one week.
- You do not have any active cancer, liver or kidney failure, or uncontrolled high blood pressure.
- You are not pregnant, breastfeeding, or planning to become pregnant during the study period.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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