Study of a drug combo and stem cell transplant for high-risk AML
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests a combination of three drugs (venetoclax, azacitidine, and homoharringtonine) followed by a donor stem cell transplant for people with intermediate- or high-risk acute myeloid leukemia (AML). The goal is to see if this approach can improve outcomes for patients who have not been treated before.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 55 years old.
- You have been diagnosed with acute myeloid leukemia (AML) that is not a subtype called APL.
- Your leukemia is considered intermediate or high risk based on medical guidelines.
- You have not received any prior treatment for leukemia, except for hydroxyurea.
- You have a suitable donor for a stem cell transplant.
- You are healthy enough for the transplant, with good heart, lung, liver, and kidney function.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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