Venetoclax and azacitidine as consolidation for high-risk AML
Part of Blood & lymphatic, Cancer clinical trials.
This trial tests the combination of venetoclax (a targeted pill) and azacitidine (a chemotherapy-like drug) as consolidation therapy after initial treatment in adults with high-risk acute myeloid leukemia (AML) who have achieved remission and are planning a stem cell transplant. The goal is to see if this combination helps prevent relapse before transplant.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have been diagnosed with high-risk acute myeloid leukemia (AML) according to standard classification.
- You are at least 18 years old.
- You have achieved complete remission or complete remission with incomplete blood count recovery after 1 or 2 cycles of venetoclax + azacitidine induction therapy.
- A suitable donor is available and you plan to undergo a stem cell transplant (from a donor).
- Your kidney, liver, and heart function are within acceptable ranges (see specific lab values).
- You are able to understand and sign the informed consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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