Comparing 3-month vs 1-month triptorelin for early puberty
Part of Hormones & metabolism clinical trials.
This study compares two treatment schedules of a puberty-blocking medicine (triptorelin) in children with central precocious puberty (early puberty). It aims to see if a 3-month injection works as well as the standard 1-month injection, while also checking effects on bone health and metabolism.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Girls: breast development before age 8 or first period before age 10; Boys: testicular growth before age 9.
- Ultrasound shows signs of early puberty (girls: ovarian follicle >4mm; boys: testicular volume ≥4 ml).
- Blood test after GnRH stimulation shows high LH (≥5 IU/L) with a specific pattern.
- Bone age is at least 1 year older than your actual age.
- Growth is faster than typical for your age.
- No prior use of puberty-blocking medications.
- Weight at least 20 kg (about 44 lbs).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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