PRG-1801 for stubborn lupus kidney and IgG4 disease
Part of Immune system & allergy, Kidney & urinary, Skin, Women’s health & pregnancy clinical trials.
This trial tests a new treatment called PRG-1801 for people with lupus nephritis (kidney inflammation from lupus) or IgG4-related disease that has not improved with standard treatments. The treatment uses your own immune cells to target and calm the disease.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 or older
- You have lupus nephritis (kidney inflammation from lupus) that is active and hasn't improved with standard treatment, OR you have active IgG4-related disease that keeps coming back or is hard to treat
- Your kidney function is at least 30% of normal (eGFR ≥ 30)
- You have not had rituximab or similar drugs in the last 6 months
- You do not have serious infections, recent heart problems, or active hepatitis B or C
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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