Combination cream vs standard cream for precancerous skin spots
Treatments studied
Part of Cancer, Skin clinical trials.
This trial tests if adding calcipotriol to a standard chemotherapy cream (5-fluorouracil) works better than the standard cream alone for treating actinic keratosis (precancerous sun-damaged skin spots). You may qualify if you have at least four spots on your face, scalp, neck, chest, or arms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have at least four actinic keratosis (AK) spots on your face, ears, scalp, neck, chest, or arms
- Your spots are mild to moderately thick (grade I–III)
- You have not had any treatment for AK in that area in the last 3 months
- You do not have skin cancer or other serious skin conditions in the treatment area
- You are not pregnant, breastfeeding, or planning to become pregnant during the study
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests if a moisturizing cream called Lipikar Baume AP+M can help with actinic keratoses (rough, scaly spots caused by sun damage) on the forearms or backs of the hands. You'll use the cream on one arm and compare it to the other arm to see if it makes a difference.
This trial tests whether applying a 30% urea cream (Lipikar) before Tolak® treatment helps treat actinic keratoses (rough, scaly spots) on the scalp. It may make the skin more receptive to the treatment.
This trial tests whether a combination of the chemotherapy cream 5-fluorouracil and an aluminum solution works well to treat actinic keratoses (precancerous sun-damaged spots) on the scalp or forearms. It may help if you have 4–15 of these spots and are generally healthy.
This trial compares two different creams used before a light-based treatment (photodynamic therapy) for actinic keratoses on the scalp. It aims to see which pre-treatment works better to clear these rough, scaly spots.
This study compares two ways to treat sun-damaged spots called actinic keratoses: freezing them (cryotherapy) or applying a chemotherapy cream (5-fluorouracil). The goal is to see which works better and is safer for people with many spots on their head, neck, arms, or legs.
This Phase 2 study compares two treatments to clear actinic keratoses (sun-caused pre-cancer skin spots) on the upper arms. If you qualify, you may get one of the study treatments and contribute to finding which one works best and is easiest to use.
Hear when a new Actinic Keratoses trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.