Clin2
NCT06501417Possibly a fitNot yet recruiting

Lynch syndrome testing for endometrial cancer

Lynch SyndromeEndometrial Cancer

Part of Cancer, Digestive system, Genetic & congenital, Hormones & metabolism, Women’s health & pregnancy clinical trials.

This study looks at a simple way to test for Lynch syndrome in people with endometrial cancer. Lynch syndrome is an inherited condition that raises the risk of certain cancers, and finding it early can help you and your family with screening and prevention.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
600 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You have endometrial cancer (cancer in the lining of the uterus) at any stage (I to IV).
  • A lab test showed your tumor has a 'mismatch repair deficiency' (dMMR), which can be a sign of Lynch syndrome.
  • You have a 'Lynch alert'—this means you or your family have features that suggest Lynch syndrome, like certain cancers at a young age.
  • You are at least 18 years old.
  • You can understand and sign a consent form to join the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06990633Not yet recruiting
Testing for Lynch syndrome in colorectal cancer surgery

This study checks tumor samples from people having surgery for colorectal cancer to look for a genetic condition called Lynch syndrome, which can increase the risk of other cancers. Finding it early can help you and your family take steps to protect your health.

NCT07194551Recruiting
Checking uterine cancer risk in Lynch syndrome with home sampling

This study is testing a new way to check for uterine cancer risk in people with Lynch syndrome. You would collect a vaginal sample yourself at home and fill out a health questionnaire, which may help catch warning signs early.

Vancouver, British Columbia
NCT07220239Recruiting
Menstrual cup for early cancer detection in Lynch syndrome

This study tests whether a menstrual cup can collect cells from the uterus to detect early endometrial cancer in women with Lynch syndrome. If you have Lynch syndrome and are due for a routine biopsy, you may be able to use a menstrual cup instead.

Boston, Massachusetts
NCT07360834Not yet recruiting
Blood test to guide cancer monitoring in Lynch syndrome

This study is testing whether a simple blood test can safely replace some of the more invasive procedures used to monitor people with Lynch syndrome, a condition that increases the risk of certain cancers (especially colorectal and uterine). If the blood test works as well, it could mean fewer colonoscopies and other invasive tests for those with Lynch syndrome.

Zagreb
NCT06582914Recruiting
Lynch syndrome genetics and health study

This study looks at the genetics and health of people with Lynch syndrome, a condition that raises the risk for certain cancers. Researchers want to learn more about how different genetic changes affect health over time.

Aurora, Colorado
NCT06708429Recruiting
Lynch syndrome and gut immune system study

This study looks at how the immune system interacts with the gut lining in people with Lynch syndrome and those without. It may help us better understand how Lynch syndrome affects the body.

Monrovia, California

Hear when a new Lynch Syndrome trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.