Checking uterine cancer risk in Lynch syndrome with home sampling
Part of Cancer, Digestive system, Genetic & congenital, Hormones & metabolism, Women’s health & pregnancy clinical trials.
This study is testing a new way to check for uterine cancer risk in people with Lynch syndrome. You would collect a vaginal sample yourself at home and fill out a health questionnaire, which may help catch warning signs early.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have Lynch syndrome, confirmed by a genetic test.
- You must still have your uterus (no hysterectomy).
- You must be 30 years old or older.
- You cannot have had endometrial cancer or a pre-cancerous condition called endometrial hyperplasia.
- You cannot have had pelvic radiation or an endometrial ablation procedure.
- You cannot be pregnant at the start or during the study.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study is testing a urine test to see if it can find bladder cancer early in people with Lynch syndrome. If you have Lynch syndrome and are between 50 and 75, this screening could help catch cancer before it causes symptoms.
This study tests whether a menstrual cup can collect cells from the uterus to detect early endometrial cancer in women with Lynch syndrome. If you have Lynch syndrome and are due for a routine biopsy, you may be able to use a menstrual cup instead.
This study is testing whether a simple blood test can safely replace some of the more invasive procedures used to monitor people with Lynch syndrome, a condition that increases the risk of certain cancers (especially colorectal and uterine). If the blood test works as well, it could mean fewer colonoscopies and other invasive tests for those with Lynch syndrome.
This study collects blood and stool samples to see how well they can detect colorectal cancer or advanced growths in people with Lynch syndrome (an inherited colon cancer risk) or suspected Lynch syndrome. It may help find cancer or precancer earlier, which can improve next-step decisions.
This study looks at a simple way to test for Lynch syndrome in people with endometrial cancer. Lynch syndrome is an inherited condition that raises the risk of certain cancers, and finding it early can help you and your family with screening and prevention.
This study tests a stool-based DNA test for people with Lynch syndrome. It aims to find colorectal cancer early by checking stool samples for specific DNA changes, so you can catch problems sooner and get the right care.
Hear when a new Endometrial Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.