Fluoxetine for Refractory Constipation with Somatic Symptoms
Treatments studied
Part of Digestive system, Mental health clinical trials.
This trial tests whether fluoxetine (a medication commonly used for mood) can help people with long-lasting constipation that hasn't improved with standard treatments, especially if they also have excessive worry about their body symptoms (somatic symptom disorder).
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must have chronic constipation (Rome IV criteria) for at least 6 months.
- You must have had 2 or fewer complete bowel movements per week during the 2-week screening period.
- You must have tried other treatments (like laxatives) for at least 3 months and not been satisfied.
- You must have a diagnosis of somatic symptom disorder (significant worry about your health or symptoms for at least 6 months).
- Your age must be between 18 and 60 years.
- You cannot be pregnant, breastfeeding, or have certain other medical conditions or medications.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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