Clin2
NCT06506136Possibly a fitNot yet recruiting

Fluoxetine for persistent constipation with somatic symptoms

Refractory ConstipationSomatic Symptom Disorder (DSM-5)Functional Constipation (FC)

Treatments studied

Part of Digestive system, Mental health clinical trials.

This trial tests whether the antidepressant fluoxetine can help people with hard-to-treat constipation who also have physical symptoms linked to stress or emotions. It may offer a new option when standard laxatives haven't worked.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
194 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You have had constipation for a while and standard laxatives haven't helped after trying at least 3 different types.
  • You have physical symptoms (like pain or bloating) that are linked to stress or emotions, and a doctor has confirmed this.
  • You are between 18 and 70 years old.
  • You have not used antidepressants, anxiety pills, or antipsychotics in the past 4 weeks.
  • You are not pregnant, breastfeeding, or planning to become pregnant during the study.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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