Treatment
Fluoxetine clinical trials
We’re tracking 21 recruiting studies that include Fluoxetine, each written for real people, not researchers, below.
Recruiting studies
- NCT03228732RecruitingEarly Phase 1
Fluoxetine and/or DHEA in people with type 1 diabetes
This early-stage study tests whether the medicines fluoxetine and/or DHEA can improve health in adults with type 1 diabetes. It’s mainly looking for people without major diabetes complications or major medical problems to safely study the effects.
Baltimore, MarylandAges 18–50 - NCT07174947RecruitingPhase 2
Fluoxetine plus immunotherapy for advanced liver cancer with depression
This study tests whether adding the antidepressant fluoxetine (Prozac) to standard immunotherapy can help treat advanced liver or bile duct cancer in people who also have depression or anxiety. You must not have received any prior cancer treatment and be ready to start immunotherapy as your first therapy.
Wenzhou, ZhejiangAges 18–80 - NCT06225011RecruitingPhase 1
Can a common antidepressant help your immune system fight colorectal cancer before surgery?
This trial is testing whether a common antidepressant called fluoxetine (Prozac) can help your immune system fight colorectal cancer before surgery. It's for people with early-stage colorectal cancer who have not yet had treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT06221722Recruiting
Brain scan study for treating constipation
This trial uses brain scans to see if doctors can predict how well constipation treatments will work. It is for adults with functional constipation, but only if they have no other digestive problems or medical implants.
Yinchuan, NingxiaAges 18–45 - NCT07424781Recruiting
Fluoxetine and emotional experience in young adults
This study looks at whether fluoxetine, a common medication for mood, affects how young adults (18-24) experience emotions. It aims to understand emotional processing in healthy individuals without psychiatric history.
Oxford, OxfordshireAges 18–24 - NCT06046859RecruitingPhase 4
Can fluoxetine help recovery after serious injuries?
This study tests whether giving the antidepressant fluoxetine (Prozac) right after a traumatic injury can help improve mental and physical recovery. It is for people who have broken bones or internal injuries from an accident and may be feeling down.
Gainesville, FloridaAges 18–85 - NCT03476525Recruiting
Study of fluoxetine after bariatric surgery
This study looks at how the antidepressant fluoxetine is absorbed and behaves in the body before and after gastric bypass or sleeve surgery. It may help doctors better predict how well fluoxetine works after weight-loss surgery.
TrondheimAges 18–70 - NCT04131829RecruitingPhase 1/Phase 2
Brain scan study to predict fluoxetine response in OCD
This study looks at how brain networks change before and after starting fluoxetine (an SSRI antidepressant) in people with obsessive-compulsive disorder (OCD). It also compares these brain scan patterns with people without OCD to help predict who may respond to treatment.
New Haven, ConnecticutAges 18–65 - NCT06898606RecruitingPhase 1/Phase 2
Psilocybin mushrooms with or without Prozac for stubborn depression
This study tests whether a dose of psilocybin (the active ingredient in magic mushrooms) can help treat depression that hasn't improved with standard antidepressants. Some participants will also take the antidepressant fluoxetine (Prozac) to see if it changes the effects.
Foz do Iguaçu, ParanáAges 25–65 - NCT05976347RecruitingPhase 4
Treatment for depression after certain bone fractures
This trial tries to find and treat depression in people who have recently had surgery for an arm, leg, or pelvis fracture. It may help by screening for depression soon after surgery and offering a new depression treatment approach if you qualify.
Winston-Salem, North CarolinaAges 18 years+ - NCT07478796RecruitingPhase 4
Blood-based dosing of SSRIs for hospitalized depression
This study tests whether adjusting the dose of common antidepressants (SSRIs) based on regular blood tests can help people in the hospital feel better faster. It is for adults and teens age 12 and older with moderate to severe depression who are starting fluoxetine, escitalopram, or sertraline.
Poznan, Greater Poland VoivodeshipAges 12 years+ - NCT07239011RecruitingPhase 1/Phase 2
Dapagliflozin for depression study
This trial tests whether dapagliflozin, a diabetes medication, can help treat major depression. It is for adults who have been depressed for at least 2 months and score high on a depression scale.
Damietta, New DamiettaAges 18–60 - NCT05814640RecruitingPhase 1/Phase 2
STAR-AD: Testing stepwise treatment for teen depression
This trial tests a step-by-step approach to treating moderate-to-severe depression in teens. It may help find a treatment path that improves mood while keeping care safe, including for some teens who have suicidal thoughts but do not need inpatient care.
Chongqing, ProvinceAges 13–18 - NCT04899687RecruitingPhase 2
Dextromethorphan for OCD and related anxiety conditions
This trial studies dextromethorphan, a medicine sometimes used for cough, to see if it can reduce symptoms in OCD and similar conditions. It may help people whose intrusive thoughts or related worries are still challenging despite current care.
Stanford, CaliforniaAges 18–65 - NCT00018057RecruitingPhase 2
Brain study of pediatric anxiety disorders
This study looks at how the brain works in children and adults with anxiety disorders. It uses brain scans (fMRI) and other safe tests to understand anxiety better.
Bethesda, MarylandAges 8–65 - NCT05041907RecruitingPhase 2
Testing an antiviral’s effects in early COVID-19
This trial looks at how well an antiviral works in the body when started early in people with COVID-19 symptoms. You may be able to join if you’re an otherwise healthy adult with confirmed infection and symptoms for less than 4 days.
Minas GeraisAges 18–60 - NCT06384209Recruiting
Friendship Bench Plus for Depression
This study tests whether a structured talk therapy program called the Friendship Bench can help adults with moderate to severe depression. You will have conversations with trained lay counselors who guide you through problem-solving techniques.
HarareAges 18 years+ - NCT06860958RecruitingPhase 3
Adding roflumilast to antidepressants for depression
This study tests if adding roflumilast, a medicine that reduces inflammation, can help people with major depression feel better when taken with their current antidepressant. It is for adults with moderate to severe depression.
TantaAges 18–65 - NCT07025590Recruiting
Exercise to help lower antidepressants for heart patients
This trial tests whether adding a structured exercise program can help people with both depression/anxiety and heart disease slowly reduce their antidepressant medication. It may offer a way to lower medication use while improving heart and mental health.
Guangzhou, GuangdongAges 18–70 - NCT00768820RecruitingPhase 4
Study brain and mental health in people with 22q11 deletion
This trial looks at how thinking and mental health (psychiatric symptoms) show up in people who have a specific chromosome deletion. It may help researchers understand patterns in this condition and improve future care.
Petah TikvaAges Any age - NCT07417046Recruiting
Fluoxetine and eye patching for lazy eye treatment
This study tests whether a combination of a medicine (fluoxetine) and eye patching can improve vision in people with lazy eye (amblyopia). It uses special eye scans and brain wave tests to see how well the treatment works for different ages.
Minya, Minya GovernorateAges 10 years+
What Fluoxetine is being studied for
Conditions with recruiting Fluoxetine studies.
Common questions
- Are there clinical trials studying Fluoxetine?
- Yes. Clin2 currently lists 21 recruiting studies that include Fluoxetine, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Fluoxetine trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Fluoxetine an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Fluoxetine or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.