Study on inherited alpha-1 antitrypsin deficiency and related liver problems
Part of Digestive system, Genetic & congenital, Lungs & breathing clinical trials.
This study looks at how alpha-1 antitrypsin deficiency affects the liver in adults. It aims to learn more about the liver problems caused by this condition and may help find better ways to manage them.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have been diagnosed with alpha-1 antitrypsin deficiency and have a specific gene type (Pi*ZZ or Pi*SZ).
- If you have the Pi*SZ type, you must have moderate to severe liver disease shown by a liver biopsy or special scans or blood tests.
- You must have had a liver biopsy, special liver scan, or blood test for liver scarring in the past 2 years, or plan to have one soon.
- You have not had a liver transplant.
- If you were in another study for liver or lung treatment, it has been at least 6 months since your last dose of the study drug.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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