Gene therapy for hearing loss from vestibular schwannoma
Part of Brain & nervous system, Cancer, Ear, nose & throat clinical trials.
This trial tests a gene therapy injected into the ear to slow tumor growth and prevent further hearing loss in people with a vestibular schwannoma that is getting worse. It's for those who already have severe hearing loss in the affected ear.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a vestibular schwannoma (a benign tumor on the hearing nerve) on one side only, and it is growing.
- The tumor is larger than 2 mm.
- You have profound hearing loss (very severe) in the ear with the tumor.
- You can follow the study schedule and agree to join a separate long-term follow-up study after this one ends.
- You have not had surgery or radiation for this tumor before.
- You do not have NF2 (a genetic condition causing tumors on both hearing nerves).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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