Beta-blocker medicine for heart recovery on ECMO
Treatments studied
Part of Heart & circulation clinical trials.
This study tests whether a medicine called esmolol (a beta-blocker) can help your heart recover while you are on a heart-lung machine (V-A ECMO). It is for adults with severe heart failure who are already on certain heart medicines.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You are on a heart-lung machine (V-A ECMO) for severe heart failure.
- The heart-lung machine was started within the last 16 hours.
- You are getting a heart-strengthening medicine called dobutamine at a dose of at least 2 mcg per kg per minute.
- You are not getting epinephrine (adrenaline) as a drip.
- Your heart rate is at least 80 beats per minute, and you are in a normal rhythm or atrial fibrillation/flutter.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial is studying whether using less of the medicines that raise blood pressure (vasopressors) can help people with severe heart failure who are on a heart-lung machine (ECMO) survive. It may answer if a gentler approach is safer.
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