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Probiotics and budesonide for IgA nephropathy

Glomerulonephritis, IGAProbioticsBudesonide

Part of Immune system & allergy, Kidney & urinary, Women’s health & pregnancy clinical trials.

This trial tests whether taking a probiotic supplement along with an enteric-coated budesonide capsule (a medicine that reduces inflammation) can help people with IgA nephropathy. It may help reduce protein in the urine and protect kidney function.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
206 people
Ages
18 years to 70 years
Study type
Interventional

Who can take part

  • You must be between 18 and 70 years old.
  • A kidney biopsy must have confirmed your IgA nephropathy.
  • Your urine protein level must be at least 0.75 grams per day (or a protein-to-creatinine ratio of 0.5 or higher).
  • Your kidney function (eGFR) must be 30 or higher (measured by a standard test).
  • You must not have taken antibiotics, steroids, other immune-suppressing drugs, or probiotic supplements in the last 3 months.
  • You must not have certain serious health conditions (like severe gut problems, cancer, heart attack, stroke, or poorly controlled diabetes).

View the official record on ClinicalTrials.gov

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Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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