Exercise for heart symptoms with clear arteries
Part of Heart & circulation clinical trials.
This trial tests if exercise training can help people who have chest pain or shortness of breath even though their main heart arteries are not blocked. It focuses on those with small vessel disease in the heart, also known as INOCA.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have normal or near-normal heart arteries without major blockages
- You have a reduced blood flow reserve in your heart's small vessels (measured by a special PET scan)
- You are not currently very physically active or have a high fitness level (VO2 max over 45)
- You are able and willing to exercise (no severe arthritis or injury that prevents it)
- You do not have heart failure (ejection fraction below 40%) or uncontrolled high blood pressure
- If you are a woman, you must be past menopause or surgically sterile
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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