Clin2
NCT06532006Possibly a fitRecruiting

HLX22 plus trastuzumab and chemo for HER2+ stomach cancer

Gastroesophageal-junction CancerMonoclonal AntibodyGastric CancerHER2-positive Gastric Cancer

Treatments studied

Part of Cancer, Digestive system clinical trials.

This trial tests adding a new drug, HLX22, to the standard combination of trastuzumab and chemotherapy for people with HER2-positive stomach or gastroesophageal junction cancer that hasn't been treated yet. The goal is to see if this three-drug mix works better than the usual two-drug approach.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
550 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 or older.
  • You have been diagnosed with HER2-positive stomach or gastroesophageal junction cancer that has spread or can't be removed with surgery.
  • You have not received any prior treatment for this cancer (except possibly neoadjuvant or adjuvant therapy if it's been more than 6 months since you completed it).
  • You have not had any prior HER2-targeted therapy (like trastuzumab or other similar drugs).
  • You are able to perform daily activities without significant help (ECOG score 0 or 1).
  • You have no active bleeding in your stomach or intestines, and no cancer spread to the brain.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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