Chemotherapy for breast cancer that spread to the brain lining
Part of Brain & nervous system, Cancer clinical trials.
This trial tests a combination of two chemotherapy drugs (thiotepa and methotrexate) given directly into the fluid around your brain and spine through a small implanted device. It aims to treat breast cancer that has spread to the lining of the brain or spinal cord.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are a woman aged 18 to 75.
- You have been diagnosed with breast cancer that has spread to the lining of your brain or spinal cord.
- You have a small device (Ommaya reservoir) implanted under your scalp to deliver medicine directly to the fluid around your brain and spine.
- Your blood counts and liver function are within safe limits (your doctor will check).
- If you are premenopausal, you must be willing to take a hormone-blocking medicine (LHRHa) during the study.
- You are not pregnant, not breastfeeding, and not currently in another clinical trial.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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