Preventing acid buildup in preterm babies on IV nutrition
Part of Genetic & congenital, Hormones & metabolism clinical trials.
This trial tests if replacing sodium chloride with sodium acetate in IV nutrition can prevent metabolic acidosis (too much acid in the blood) in preterm babies born before 33 weeks. If your baby is in the NICU and needs IV nutrition, this study may help keep their blood chemistry balanced.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your baby is born before 33 weeks of pregnancy
- Your baby needs intravenous nutrition (PN) during the first 28 days of life
- You (as parent or legal guardian) give written permission for the study
- Your baby does not have a genetic metabolic disorder
- Your baby does not have severe liver failure or a serious birth defect needing multiple surgeries
- Your baby does not have very high blood sodium (above 150) or severe blood alkalinity
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests if giving sodium bicarbonate helps critically ill patients who have both metabolic acidosis (too much acid in the blood) and acute kidney injury (sudden kidney trouble). It aims to see if this treatment can improve outcomes.
This trial compares two medicines, THAM and sodium bicarbonate, to treat metabolic acidosis (too much acid in the blood) after heart surgery that used a heart-lung machine. The goal is to see which medicine works better for patients in this situation.
This trial tests whether adding sodium and fortified milk to nutrition helps very premature babies grow stronger and develop healthier body composition. Researchers will measure growth and body fat over time to see if these additions improve outcomes.
This study looks at whether tracking sodium levels in breast milk can help mothers of preterm babies improve their milk supply. If you are a new mom who gave birth before 35 weeks and plan to pump for at least two weeks, this trial may help you learn more about your milk.
This trial tests whether an oral medicine called N-acetylcysteine (NAC) is safe and well-tolerated in infants with biliary atresia. It looks for participants who are 4–9 months old, can eat and take medicines by mouth, and will stay in the hospital for at least 4 days.
This trial looks at how to best treat newborns with very high ammonia in the blood when urgent dialysis is needed. It may help doctors choose the most effective way to rapidly lower ammonia and improve outcomes in babies with certain inherited metabolic conditions.
Hear when a new Metabolic Acidosis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.