Clin2
NCT06546683Worth exploringNot yet recruiting

How gut-derived fatty acids affect brain activity

StressHealthy Volunteers

Part of Mental health clinical trials.

This study tests how short-chain fatty acids (natural compounds made by gut bacteria) affect brain activity in healthy men. You would get a supplement and undergo brain scans to see if it changes how your brain responds.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
32 people
Ages
18 years to 45 years
Study type
Interventional

Who can take part

  • You must be a man between 18 and 45 years old.
  • Your body mass index (a measure of body size) should be between 18.5 and 25.
  • You need access to a home freezer that is set to at least 0°F (-18°C).
  • You must be in good health with no history of brain, psychiatric, stomach, or hormone conditions.
  • You cannot be a smoker, work night shifts, or take certain medications (like antibiotics or steroids) within the last 3 months.
  • You cannot have recently (within 1 month) had an infection, vaccination, or used pre/probiotic supplements.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06620679Recruiting
Brain inflammation and stress in healthy men

This study explores how inflammation in the body affects the brain's response to stress. Healthy men will have brain scans and stress tests to understand this link better.

Leuven, Flemish Brabant
NCT05587036Recruiting· Phase 2/Phase 3
Rifaximin study to see how gut bacteria affect mood

This trial tests whether a gut-targeting antibiotic called rifaximin changes the gut microbiome (gut bacteria) and affects emotion. It is looking for healthy men so any mood or gut changes can be more clearly linked to the study treatment.

Leuven
NCT06243783Recruiting
Stress and Brain Energy: A Healthy Volunteer Study

This study looks at how stress affects your brain's energy use. It involves an MRI scan and is for healthy, right-handed adults aged 18–40.

Vienna
NCT07713641Recruiting
Testing gut bacteria's effect on brain function and inflammation

This trial looks at whether short-chain fatty acids (substances made by gut bacteria) can reduce inflammation and improve thinking skills (executive function). You'll receive an injection that causes mild, temporary inflammation (like a bad cold) and complete cognitive tasks.

Leuven
NCT07355309Not yet recruiting
High-dairy diet and gut-brain health study

This study looks at how eating more dairy foods affects the connection between your gut and your brain. It may help improve your overall health if you are overweight or obese.

Maastricht, Limburg
NCT04328337Recruiting· Phase 1/Phase 2
Study tests how rising fatty acids affect brain fuel use

This early-phase study will raise fatty acid levels temporarily and see how the brain uses glucose (sugar) and processes energy. It may help researchers understand how metabolism in the body can change brain function.

Chapel Hill, North Carolina

Hear when a new Stress trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.