Clin2
NCT06548204Possibly a fitRecruiting

Antihistamine after a heart attack

ST-segment Elevation Myocardial Infarction (STEMI)

Part of Heart & circulation clinical trials.

This trial tests whether taking an antihistamine medicine called fexofenadine hydrochloride can help people recover better after a heart attack. It is a randomized study, so some participants will receive the medicine and others will receive a placebo (a pill with no active ingredients).

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
160 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years old or older.
  • You had a type of heart attack called STEMI, confirmed by chest pain, blood tests, and ECG changes.
  • You had emergency heart procedure (coronary angiography) to open a blocked artery.
  • An ultrasound of the heart showed your heart pump function is reduced (LVEF at or below 50%).
  • You have not had a previous heart attack, heart bypass surgery, or long-term use of fexofenadine or similar allergy medicines.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT04912518Recruiting
Dexmedetomidine for heart protection after a specific heart attack

This study tests whether dexmedetomidine can protect the heart in people who are having a specific type of heart attack (anterior STEMI) when treated within 6 hours of symptom start. You may be considered if your diagnosis and vital signs fit the study safety rules, and if you can take part in follow-up.

Hefei, Anhui
NCT06704685Not yet recruiting· Phase 3
Butylphthalide to reduce heart damage after a heart attack

This trial tests whether a drug called butylphthalide, given with a stent procedure, can reduce heart damage and improve recovery after a heart attack. You may join if you are having a heart attack and can get treated quickly.

NCT07536802Recruiting· Phase 4
Adenosine Safety and Benefit in Emergency Heart Attack Treatment

This study tests whether giving a medication called adenosine before emergency heart catheterization (a tube procedure to open blocked arteries) helps patients having a heart attack. Adenosine may protect heart tissue and improve outcomes.

Karachi, Sindh
NCT07381803Recruiting· Phase 3
Fexofenadine for heart attack recovery

This trial tests if the allergy medicine fexofenadine can improve recovery after a heart attack. You may qualify if you had a specific type of heart attack (STEMI) within the last week.

Hangzhou, Zhejiang
NCT07153744Not yet recruiting· Phase 4
Chinese medicine for recent heart attack

This trial adds a Chinese medicine (Shexiang Baoxin Pill) to standard care for people having a heart attack, to see if it improves recovery when taken alongside the usual artery-opening procedure. It may help speed up heart recovery and reduce further damage.

Shanghai
NCT07776288Not yet recruiting· Phase 2
Antioxidant therapy after a first heart attack

This trial tests whether giving a combination of antioxidant vitamins (supplements) during emergency treatment for a first heart attack can reduce heart muscle damage and improve recovery. You might be eligible if you are having an emergency angioplasty for a recent heart attack.

Santiago, Santiago Metropolitan

Hear when a new ST-segment Elevation Myocardial Infarction (STEMI) trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.