Knee osteoarthritis treatment study with cell therapy
Part of Bones, joints & muscles clinical trials.
This trial tests a new cell-based treatment (CLS2901C) for knee osteoarthritis. It combines the treatment with a realignment surgery (proximal tibial osteotomy) to help repair cartilage damage and reduce pain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 20 and 79 years old
- You have knee osteoarthritis (Kellgren-Lawrence grade 2 to 4) and qualify for a specific realignment surgery
- Your knee can bend at least 120 degrees and straighten to within 5 degrees of full extension
- A cartilage defect in your knee is at least 4 square centimeters (about the size of a quarter), and total defects are no larger than 21 square centimeters
- Your body mass index (BMI) is under 30
- You haven't had certain prior knee surgeries (like ligament reconstruction, meniscus repair, or cartilage treatments) or cell-based therapies in your target knee
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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