Better HER2 testing for HER2-low breast cancer on Enhertu
Part of Cancer clinical trials.
This study looks at using a more detailed lab test to measure HER2 levels in people with HER2-low metastatic breast cancer who are starting or have just started treatment with Enhertu. The goal is to see if this test can help doctors better understand who might benefit from Enhertu.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years old or older.
- You have metastatic breast cancer that is HER2-low (specifically 1+ on a standard lab test).
- You plan to start or have recently started treatment with Enhertu (T-DXd).
- You have a stored tumor sample from a recent biopsy (not from a bone sample that was decalcified).
- You do not have HER2-positive breast cancer (3+ or 2+ with a positive FISH test).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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