Natural history study of genetic blood vessel disease
Part of Genetic & congenital, Heart & circulation clinical trials.
This study tracks the health of people with a confirmed ACTA2 gene change over time to better understand the disease. It may help researchers learn how to improve care for this condition.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed change in the ACTA2 gene
- Your medical records since birth are available
- Both parents or legal guardians speak English and can give consent
- You are able to travel to the study site
- You are not pregnant
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study collects extra blood (and sometimes tissue during procedures) to look for markers that can help doctors better understand vascular anomalies. It may not be a treatment, but it can improve future care by finding patterns linked to the condition.
This study looks at people with a mutation in the COL4A1 or COL4A2 genes, which can cause problems in small blood vessels throughout the body. It aims to learn more about the condition and may also include family members who carry the mutation or who can serve as healthy controls.
This study collects blood samples and medical information from people with rare inherited blood vessel diseases of the brain, and from healthy volunteers. Researchers use this information to understand these diseases better and develop future treatments.
This trial studies CADASIL (a genetic blood-vessel condition in the brain) by following people over time with MRI scans, blood draws, and questionnaires. It may help researchers better understand how the condition changes and how factors like medications affect outcomes.
This study looks at genetic (inherited DNA) factors in people with certain abnormal blood vessel connections in the brain or spinal cord. It may help researchers understand why these malformations happen and how they might behave over time.
This study collects blood (and sometimes tissue samples) from people who may have vascular (blood vessel) problems and from certain pregnant participants. Researchers use the samples to better understand vascular disease and to help guide future research.
Hear when a new Multisystemic Smooth Muscle Dysfunction Syndrome trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.