Treatment
Plasma Exchange clinical trials
We’re tracking 18 recruiting studies that include Plasma Exchange, each written for real people, not researchers, below.
Recruiting studies
- NCT06562803Recruiting
Cleaning the blood for liver failure with sepsis
This trial tests if a special blood-filtering method combined with plasma exchange can help people with severe liver failure and sepsis. It aims to reduce inflammation and improve survival.
Guangzhou, GuangdongAges 18–70 - NCT07707739Recruiting
Plasma exchange for children with autoimmune encephalitis
This trial tests whether plasma exchange (a procedure that cleans the blood) can help children with a severe form of autoimmune encephalitis—a condition where the immune system attacks the brain. It's for children who haven't gotten better with standard treatments like steroids or IVIG.
Shibīn al Kawm, Menoufia GovernorateAges 1 month–18 years - NCT05093075RecruitingPhase 2
Plasma exchange for ICU patients with severe septic shock
This study tests whether therapeutic plasma exchange (a procedure that removes and replaces blood plasma) can improve outcomes in ICU patients with septic shock that is not responding to standard medicines. It may help some people whose infection-related illness is causing failing organs.
Calgary, AlbertaAges 16 years+ - NCT07706413Recruiting
Plasma exchange for children with severe sepsis
This trial tests whether removing harmful substances from the blood (plasma exchange) can help children with severe infections that cause organ failure or very low blood pressure. If your child is in the hospital with severe sepsis or septic shock and is between 1 month and 18 years old, this treatment might be an option.
Shibīn al Kawm, Menoufia GovernorateAges 1 month–18 years - NCT05726825Recruiting
Add-on plasma exchange for new septic shock
This study tests whether adding plasma exchange (a blood-cleaning treatment) to usual care can improve outcomes for people with new septic shock. If you qualify, you may receive this treatment soon after septic shock is diagnosed to help your body recover.
InnsbruckAges 18–80 - NCT04871035Recruiting
Compare immunoadsorption vs plasma exchange for Guillain-Barré
This study tests whether immunoadsorption works as well as plasma exchange to improve symptoms in people with Guillain-Barré syndrome. The goal is to find which treatment helps recovery and is safer for patients.
Ulm, Baden-WurttembergAges 18 years+ - NCT07158463Recruiting
Plasma exchange in children with kidney disease
This study looks back at kids aged 1–18 who had a treatment called therapeutic plasma exchange (TPE) in the pediatric kidney unit. TPE is a procedure that replaces the liquid part of the blood, which may help with certain kidney conditions.
SohagAges 1–18 - NCT06382675Recruiting
Testing a new plasma filter for blood cleaning treatment
This trial tests a new plasma filter, PX2, used in a procedure called therapeutic plasma exchange (TPE) to clean harmful substances from your blood. It’s for people who already need TPE and can safely use a blood thinner during the treatment.
Aschaffenburg, BavariaAges 18 years+ - NCT06291025Recruiting
Testing a simpler treatment for immune-mediated TTP
This study is testing a new combination of medicines—immune-suppressing drugs, caplacizumab, and plasma infusions—to treat immune-mediated TTP without standard plasma exchange. It aims to make treatment simpler and potentially safer.
AmiensAges 18 years+ - NCT06831643Recruiting
Comparing two types of plasma exchange for children with sudden liver failure
This trial tests whether a higher volume of plasma exchange (cleaning the blood to remove toxins) works better than the standard amount for children with acute liver failure who are not improving with usual care.
New Delhi, National Capital Territory of DelhiAges 3–18 - NCT06362967RecruitingPhase 2
Lowering high antibodies before stem cell transplant
This trial tests a special treatment to lower high levels of anti-HLA antibodies before a stem cell transplant. The goal is to help the transplant succeed and reduce the risk of rejection.
Hefei, AnhuiAges 14–60 - NCT06571552Recruiting
Comparing two blood filtering methods' effect on clotting
This study compares two ways of filtering your blood (plasmapheresis) to see how each affects your blood's ability to clot. If you already receive regular plasmapheresis with citrate, you might help doctors learn which method is safer for you.
NîmesAges 18 years+ - NCT07420296RecruitingPhase 3
Modified zipper therapy for AQP4-positive neuromyelitis optica
This trial tests a new treatment called modified zipper therapy for people with neuromyelitis optica spectrum disorder (NMOSD) who have a specific antibody (AQP4-IgG) in their blood. It aims to stop a recent attack and improve recovery.
TianjinAges 18–80 - NCT07329036Recruiting
Liver support therapy for acute liver failure
This trial tests two different blood-filtering treatments for people with severe liver failure who are waiting for or unable to receive a liver transplant. It aims to see how these treatments affect blood clotting, inflammation, and organ function.
PragueAges 18–75 - NCT07197099Recruiting
Plasma exchange for immune-related nerve diseases
This study looks at whether removing and replacing blood plasma (called therapeutic plasma exchange or TPE) can help people with immune-related nerve or brain conditions. It includes both new and returning cases that meet standard guidelines for this treatment.
CairoAges Any age - NCT07100990RecruitingPhase 3
Early versus rescue plasma exchange for optic neuritis or transverse myelitis
This study tests whether starting plasma exchange early (right after steroids) is better than waiting to see if steroids are enough for people with severe optic neuritis or transverse myelitis. It may help preserve vision or movement by stopping inflammation sooner.
Birmingham, AlabamaAges 18 years+ - NCT07087860RecruitingPhase 2
Plasma exchange plus targeted therapy for advanced bladder cancer
This trial tests a procedure called therapeutic plasma exchange (TPE) combined with the drugs enfortumab vedotin and pembrolizumab for people with advanced bladder cancer that has stopped responding to standard treatments. The goal is to see if TPE helps the drugs work better.
Rochester, MinnesotaAges 18 years+ - NCT05004493Recruiting
Plasma exchange patient registry and sample collection
This study collects information and blood or other samples from people who are getting plasma exchange therapy. The goal is to build a registry (a organized database) that researchers can use to better understand and improve care.
Iowa City, IowaAges 12–99
What Plasma Exchange is being studied for
Conditions with recruiting Plasma Exchange studies.
Common questions
- Are there clinical trials studying Plasma Exchange?
- Yes. Clin2 currently lists 18 recruiting studies that include Plasma Exchange, drawn from the U.S. registry and rewritten for real people so you can see what each is testing and who it's for.
- How do I know if I qualify for a Plasma Exchange trial?
- Each study lists its own eligibility criteria — rules about condition, age, and prior treatments. On every Clin2 trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Is Plasma Exchange an approved treatment?
- A drug being studied in a trial may be investigational (still being tested) or already approved and being studied for a new use. Each study page explains what phase it's in. Clin2 does not provide medical advice — talk with your doctor about whether Plasma Exchange or a specific trial is right for you.
Related treatments
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. A drug appearing here is being studied in a trial and may be investigational. Talk with your doctor about whether a specific treatment or trial is right for you.