Gene tests and blood test to guide melanoma treatment
Part of Cancer, Skin clinical trials.
This study looks at your melanoma's gene activity and a blood test for tumor DNA to help predict the risk of the cancer coming back. You will need to provide blood and tissue samples, and the goal is to find better ways to personalize treatment for people with thicker, high-risk melanomas.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You must have a confirmed diagnosis of melanoma (a type of skin cancer).
- Your melanoma must be thicker than 2 millimeters (about the size of a pencil eraser) and have not spread to lymph nodes or other organs.
- Your tumor must have been tested for certain gene changes (BRAF, NRAS, and KIT).
- You are scheduled to have a sentinel lymph node biopsy (a procedure to check if cancer has spread).
- You must agree to provide blood and tissue samples for research.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study looks at serial (repeated) tumour biopsies and blood samples in people with advanced melanoma. The goal is to understand biomarkers and disease changes over time, which may help improve future treatment decisions.
This study tests if giving you targeted therapy pills (encorafenib and binimetinib) only when a blood test shows your cancer is active — instead of continuously — can help keep the melanoma under control with fewer side effects. It is designed for people with advanced melanoma that has a BRAF mutation.
This trial is looking at a protein called CD160 on immune cells (NK cells) in melanoma patients. The goal is to understand if this protein can be a target for new treatments. By studying your blood and tumor samples, researchers hope to find better ways to treat advanced melanoma.
This trial uses special lab tests to look for tumor “molecular fingerprints” in your tumor or blood sample. The goal is to help your care team choose more personalized treatment options based on those results.
This study tests the genes of your cancer to learn more about advanced breast, lung, melanoma, or sarcoma tumors. It may help doctors find better ways to treat these cancers in the future.
This trial is testing a new way to predict which immunotherapy might work best for your cancer. It uses a sample of your tumor to look for personal markers, so your treatment can be tailored to you.
Hear when a new Melanoma trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.