Clin2
NCT06570213Possibly a fitRecruiting

Neck injection plus talk therapy for PTSD

PTSD

Treatments studied

Part of Mental health clinical trials.

This study tests whether a combination of a neck injection (stellate ganglion block) and a talk therapy called Cognitive Processing Therapy helps treat PTSD better than either alone. Participants will get two injections two weeks apart, plus a week of daily therapy sessions.

Summary written for real people, not researchers, by Clin2.

Phase
Early Phase 1
Enrollment
270 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 or older
  • You have been diagnosed with PTSD by a doctor
  • You have a smartphone you can use for the study
  • You are willing to get 2 injections in the neck (or placebo) 2 weeks apart
  • You are willing to do daily therapy or monitoring for one week

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05700279Recruiting
PTSD treatment to help prevent future chronic pain

This study tests whether treating post-traumatic stress disorder (PTSD) right when you come to the emergency room for new, acute pain can lower the chance you develop long-term (chronic) pain. It may help people whose pain and trauma symptoms start around the same time.

Chicago, Illinois
NCT07087015Not yet recruiting
Nerve block for treating PTSD

This study tests if a cervical sympathetic block, an injection near certain neck nerves, can reduce PTSD symptoms. It may help if you have had PTSD for a while and are looking for new treatment options.

NCT05427500Enrolling by invitation· Phase 3
Nerve block treatment for PTSD with strong stress-and-alertness symptoms

This Phase 3 study tests whether a procedure called a stellate ganglion block can reduce PTSD symptoms, especially feeling highly “on edge” (hyperarousal). You may join if you have PTSD despite appropriate usual treatments and are able to go through the procedure safely.

Ottawa, Ontario
NCT07382596Recruiting· Phase 4
Cervical injections for treatment-resistant PTSD

This study tests if injecting a sugar-water solution around neck nerves can help PTSD that hasn't improved with standard treatments. Half the participants get sugar-water, half get salt-water, and you'll be assigned to usual care for 3 months first.

Lexington, Kentucky
NCT07473505Recruiting
Nerve block for PTSD in special operations veterans

This study tests if a specific nerve block (cervical sympathetic block) can help reduce trauma-related symptoms in Special Operations veterans with PTSD. The goal is to see if this treatment is safe and can improve how you feel.

Strongsville, Ohio
NCT07523685Recruiting
Vagus Nerve Stimulation for PTSD Treatment

This study tests a non-invasive device that stimulates the vagus nerve (a major nerve in your neck) to help reduce PTSD symptoms. The device is worn on the skin and may help ease trauma-related stress and anxiety.

Sunnyvale, California

Hear when a new PTSD trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.