Catheter plus vein ablation for atrial fibrillation with heart failure
Part of Heart & circulation clinical trials.
This trial tests whether adding a vein ablation to standard catheter ablation helps people with persistent atrial fibrillation and heart failure. It aims to find the best treatment to improve heart function and reduce symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 80 years old.
- You have had persistent atrial fibrillation for at least 6 months, lasting more than 7 days without going back to normal rhythm, and have had at least two episodes in the last 6 months even after treatment.
- You have heart failure with a left ventricular ejection fraction (pumping strength of the heart) of 40% or less.
- You are willing to take medication or have surgery, and you can complete a 6-minute walk test.
- You are not pregnant and (if applicable) have a negative pregnancy test.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether early catheter ablation (a procedure to fix irregular heartbeats) helps people who have both heart failure and atrial fibrillation. It looks at how this treatment affects your heart function and quality of life.
This trial tests if a pacemaker plus an ablation procedure can improve heart failure symptoms in people with atrial fibrillation. It is for those with moderate to severe heart failure who are already on the right medications.
This trial compares two ways to help stop atrial fibrillation during a repeat procedure: standard vein isolation only versus standard isolation plus an added medicine (ethanol) into the vein of Marshall. It aims to see whether the added step improves results when atrial fibrillation returns after a previous successful treatment.
This trial tests whether a catheter procedure that treats atrial fibrillation works better than standard care for people with heart failure with preserved ejection fraction. It aims to improve heart rhythm symptoms and overall outcomes compared with conventional treatment.
This trial tests whether a procedure called catheter ablation (which fixes the heart's electrical signals) can help people with heart failure and atrial fibrillation. It focuses on those whose heart pumping strength is mildly reduced or preserved (above 40%).
This study tests a new approach to catheter ablation for people with persistent atrial fibrillation (a type of irregular heartbeat). It may be an option if you have not responded well to or could not tolerate a rhythm-control medication.
Hear when a new Heart failure trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.