Pacemaker and ablation for heart failure with atrial fibrillation
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests if a pacemaker plus an ablation procedure can improve heart failure symptoms in people with atrial fibrillation. It is for those with moderate to severe heart failure who are already on the right medications.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have permanent or persistent atrial fibrillation (a type of irregular heartbeat).
- You have heart failure symptoms that make you short of breath or tired during daily activities (NYHA Class II to IVa).
- You have been on guideline-directed heart failure medications for at least 3 months.
- If you are under 75, a blood test (NT-proBNP) must be 600 or higher; if 75 or older, 900 or higher (or 600 if you were hospitalized for heart failure in the last year).
- You do not have severe mobility issues (like being wheelchair-bound) or other serious health problems that would limit your participation.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a special pacing method (conduction system pacing) combined with a small ablation to control heart rate in people with permanent atrial fibrillation and advanced heart failure. It aims to improve symptoms and potentially avoid the need for a heart transplant or LVAD.
This study compares two treatments for people with atrial fibrillation and heart failure: one is a procedure to fix the irregular heartbeat (AF ablation), and the other involves a different type of pacing for the heart. It aims to find which approach helps you feel better and stay out of the hospital.
This trial tests a new type of pacemaker for people with atrial fibrillation who are scheduled for a procedure that disconnects the heart's natural electrical pathway. It may help improve symptoms and heart function.
This trial tests whether a procedure called catheter ablation (which fixes the heart's electrical signals) can help people with heart failure and atrial fibrillation. It focuses on those whose heart pumping strength is mildly reduced or preserved (above 40%).
This trial tests whether a catheter procedure that treats atrial fibrillation works better than standard care for people with heart failure with preserved ejection fraction. It aims to improve heart rhythm symptoms and overall outcomes compared with conventional treatment.
This study tests a new approach called 'Ablate and Pace HIS' for people with atrial fibrillation and heart failure who haven't improved with other treatments. It combines a heart ablation procedure with a special type of pacing to help your heart pump more efficiently and reduce symptoms.
Hear when a new Atrial fibrillation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.