Leucine for midlife depression
Part of Mental health clinical trials.
This study tests whether leucine, a common amino acid supplement, can help treat moderate to severe depression in people aged 40–65. You'll have blood tests, an MRI, and a lumbar puncture to measure changes in your brain.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 40 and 65 years old.
- You have moderate to severe depression (confirmed by a study interview).
- You have a body mass index (BMI) between 20 and 35.
- You are willing to have an MRI and a spinal tap (lumbar puncture).
- You haven't taken antidepressant medications in the last 4 weeks (or 8 for fluoxetine).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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