Lactate therapy for major depression
Treatments studied
Part of Mental health clinical trials.
This study tests if adding lactate to standard depression treatment helps improve symptoms in people recently hospitalized for depression. Lactate is a natural substance that may have a positive effect on brain function.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 65 years old.
- You are currently hospitalized for depression (within the last week).
- You have moderate to severe depression symptoms.
- You have had 3 or fewer depressive episodes in your lifetime.
- You are on 3 or fewer psychiatric medications and 4 or fewer total medications.
- You are willing to have a small tube in your arm for 5 days for the treatment.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This Phase 2 trial tests whether an NMDA-targeted treatment can improve symptoms of major depressive disorder (MDD). You may be able to join if your depression diagnosis and symptom score fit, and you meet several safety and study-following requirements.
This trial studies an NMDA-based treatment for people with major depressive disorder who did not respond to at least one antidepressant. It may help by changing brain signaling linked to depression symptoms.
This study tests whether adding magnesium bisglycinate (a mineral supplement) to your current antidepressant medication can help improve depression symptoms. Researchers want to see if this combination works better than antidepressant alone.
This trial studies a way to change how excitable the brain is (through in-person brain stimulation) in people with major depression. It may help understand new treatments or symptom patterns that could be useful for major depression.
This study tests if laughing gas (nitrous oxide) can help improve mood in people with major depression. You will receive either laughing gas or a placebo, and your mood will be monitored over time.
This study tests whether adding lumateperone to an antidepressant helps adults with major depressive disorder (MDD) who haven’t improved enough after trying at least two different antidepressants. It may help reduce depressive symptoms more than antidepressants alone.
Hear when a new Major Depressive Disorder trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.