DNA methylation changes as we age
Part of Heart & circulation clinical trials.
This study looks at how DNA methylation (a type of chemical change in your DNA) changes with age, and whether heart failure with preserved ejection fraction (a type of heart failure) affects these changes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Be a healthy adult between 18 and 40 years old
- Be 65 or older and have no signs of heart failure
- Be 65 or older and have a diagnosis of heart failure with preserved ejection fraction (your heart's pumping strength is over 50%)
- Not have heart failure with reduced or mildly reduced pumping strength (under 50%)
- Not have a history of cancer or inflammatory diseases
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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