Tirofiban to prevent stroke worsening after clot buster
Treatments studied
Part of Brain & nervous system, Heart & circulation clinical trials.
This study tests whether a medication called tirofiban can help prevent stroke symptoms from getting worse after receiving a clot-busting drug. It is for patients with a narrowed brain artery and ongoing moderate to severe symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years of age or older.
- You had a stroke caused by a clot, and you received a clot-busting medication within 4.5 hours of symptom onset.
- At least 1 hour after the clot buster, you still have moderate to severe stroke symptoms (NIHSS score of 5 or more).
- A brain scan after the clot buster shows a narrowed brain artery (50-99%) due to atherosclerosis (hardening of the arteries).
- You did not have any bleeding in the brain after the clot buster, and you were not already on blood thinners before the stroke.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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